Post Cycle Therapy (PCT)

The PCT program outlined below was developed by the doctors at the Program for Wellness Restoration (PoWeR), who have a formidable history helping patients recover normal hormonal functioning following steroid therapy. One of the key doctors on this program, Dr. Michael Scally, claims to have successfully treated more than 100 cases of hypogonadism/hypogonadotrophic hypogonadism, and is very well known in the field of androgen replacement therapy. PoWeR published this program as part of a recent clinical study, which involved 19 healthy male subjects who were taking supraphysiological (highly suppressive) doses of testosterone cypionate and nandrolone decanoate for 12 weeks. Their HPGA Normalization Protocol focuses on the combined use of HCG, Nolvadex' and Clomid, and is perhaps the only clinically documented post-cycle therapy program to be found in the medical literature.

Examining the program closely, we note that the testes are hit hard with HCG at the onset of therapy. Its intake however, is limited to only 20 days. The doctor, undoubtedly recognize that when HCG is taken for too long or at too high a dosage, it can desensitize the LH receptor. This would only further exacerbate the post cycle problem, not help it. Anti-estrogens are used during and after HCG, with a dosage of 20 mg of Nolvadex (Tamoxifen) twice daily and 50 mg of Clomid twice daily rounding out this compliment of drugs. Clomid is used for a shorter period of time than Nolvadex, likely because of the desensitizing effect it too can have (on the pituitary gland) with continued use. Among other things, these two anti-estrogens will continue to foster LH release as testosterone levels start to go back up, as well as combat any potential estrogenic side effects that may be caused by HCG's up-regulation and testicular aromatase activity. Although in the first couple of weeks the anti-estrogens probably do very Iittlle as they should be much more helpful towards the middle and end of the program. During this clinical investigation: normal hormonal function was restored in all subjects,I within 45 days of drug cessation.